Identification of locally correlated clusters of epigenetics features (e.g., peaks of open chromatin).
Identifying functional variants underlying disease risk and adoption of personalized medicine are currently limited by the challenge of interpreting the functional consequences of genetic variants. Predicting the functional effects of …
An unified resource of genome (SNP array), transcriptome (RNA-seq) and epigenome (ATAC-seq) datasets from CommonMind consortia.
An unified resource of genome (WGS/WES), transcriptome (RNA-seq) and proteome from MSBB AMP-AD consortia.
Here, we generated ATAC-seq atlas from 14 brain regions and two cell types of human brains.
Complex protein engineering portal combining sofware tools from multiple consortia members.
Webserver for design of enzyme mutations for improving their thermal stability.
One-stop-shop portal for protein engineers aiming to improve protein stability, activity, and/or enantioselectivity.
Meta-predictor of the effect of nucleic acid substitution on human health (rare diseases).
New approach for improving thermal stability of enzymes.