Source Themes

NewProt - a protein engineering portal

Complex protein engineering portal combining sofware tools from multiple consortia members.

FireProt: web server for automated design of thermostable proteins

Webserver for design of enzyme mutations for improving their thermal stability.

HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering

One-stop-shop portal for protein engineers aiming to improve protein stability, activity, and/or enantioselectivity.

PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions

Meta-predictor of the effect of nucleic acid substitution on human health (rare diseases).

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

New approach for improving thermal stability of enzymes.

Maximizing the efficiency of multienzyme process by stoichiometry optimization

General approach for optimizing the stoichiometry in a pathway with an engineered enzyme.

Computational tools for designing smart libraries

Review of protein engineering approaches and software tools.

Computer-assisted engineering of the synthetic pathway for biodegradation of a toxic persistent pollutant

Assembly of a synthetic route for toxic 1,2,3-trichloropropane to glycerol in E. coli.

PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations

General meta-predictor of the effect of amino acid substitution on the protein function (not limited to humans).