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Here, the authors perform ATAC-seq on four distinct cell populations from three different regions of the human brain, finding that chromatin accessibility varies greatly by cell type and less by brain region. This study reveals differences in biological function and gene regulation, as well as overlap of genetic variants associated with schizophrenia and other neuropsychiatric traits.

A comprehensive evaluation of genomic interaction of schizophrenia with other medical conditions derived from HiC interactions within midbrain dopaminergic neurons.

Identification of locally correlated clusters of epigenetics features (e.g., peaks of open chromatin).

Identifying functional variants underlying disease risk and adoption of personalized medicine are currently limited by the challenge of interpreting the functional consequences of genetic variants. Predicting the functional effects of …

An unified resource of genome (SNP array), transcriptome (RNA-seq) and epigenome (ATAC-seq) datasets from CommonMind consortia.

An unified resource of genome (WGS/WES), transcriptome (RNA-seq) and proteome from MSBB AMP-AD consortia.

Here, we generated ATAC-seq atlas from 14 brain regions and two cell types of human brains.

Complex protein engineering portal combining sofware tools from multiple consortia members.

Webserver for design of enzyme mutations for improving their thermal stability.

One-stop-shop portal for protein engineers aiming to improve protein stability, activity, and/or enantioselectivity.